Regarded as one of the most effective brain nutrients in the world, Chemi Nutra offers AlphaSize® Alpha-Glyceryl Phosphoryl Choline: it is often used to support memory and in sports medicine and nutrition programs to enhance muscular power output, sharpen agility, and delay fatigue.

This is because of its innate ability to activate mental acuity and muscle fibers (as well as contract them).

AlphaSize® is an advanced choline compound that supports brain metabolism by promoting the release of acetylcholine, the body and brain’s primary neurotransmitter chemical. This is why it is often considered a mind-to-muscle ingredient.

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Manufactured By: Chemi S.p.A

Since: 2001

Made in Italy

Health Benefits

Our AlphaSize® A-GPC promotes the neurotransmitter acetylcholine (AC) and neuromuscular optimization to support brain and body functions such as:

Muscular Power
Hand-Eye Coordination

It also promotes youthfulness, vitality, and body composition.

You and your clients will notice a positive difference in your performance during work, workouts, and everyday tasks when you use AlphaSize® A-GPC.


Available in several powdered forms for different application purposes, Chemi Nutra’s AlphaSize® A-GPC is Kosher Certified, Halal Certified, USP grade, NDI, GRAS-affirmed, and is 100% water-soluble leaving no taste. Use our nutritious, health-benefit-loaded ingredient in:

Dietary Supplements
Functional Foods
Medical Foods
Functional Beverages

Long-term product applications will support mental performance, energy, and vitality. At Chemi Nutra, we create nutrients for a better quality of life.

Scientific Information

AlphaSize® Alpha-Glyceryl Phosphoryl Choline (A-GPC) provides an immediate supply of choline to the bloodstream. Choline is an essential component of all major phospholipids in our bodies. Choline undergoes a process called acetylation, resulting in the formation of acetylcholine, which is one of the most important neurotransmitters in the central nervous system, and responsible for the transmission of communication impulses between neurons.

A-GPC crosses the blood-brain barrier to boost choline levels in the brain, and it is involved in the synthesis and release of acetylcholine (AC). This boost of choline and release of AC supports cognitive functioning.

A-GPC provides a rapidly absorbed form of choline that has been shown to raise free plasma choline levels faster than other choline precursors. Since A-GPC is incorporated into brain phospholipids within 24 hours following absorption, the beneficial memory enhancing effects are fast and noticeable.

In addition, through sophisticated metabolic processes, choline potentiates the secretion of human growth hormone (HGH), a master hormone that in part supports basal metabolism and hence body composition.

As we age, the amount of HGH we produce steadily declines. It is well accepted that by age 60, serum HGH levels can often be 1/10th of the HGH levels seen at age 25. Like other hormones critical to the functioning of the body, HGH diminishes with advancing age in similar fashion as many other important hormones.

AlphaSize® A-GPC is considered to be an effective “GH secretagogue”, and therefore has potential to be one of the most significant agents to help maintain healthful body composition, help retain lean muscle mass and strength, help reduce fat mass, and help maintain youthful vigor.

During intense exercise, stress and physical activity, choline becomes a limiting factor in the formation of AC, the motor unit’s primary neurotransmitter, thus diminishing AC release at the neuromuscular junction and negatively affecting peak performance.

Ask Us About AlphaSize® A-GPC

Reach out to the Chemi team to find out more about what our AlphaSize® A-GPC and other products can help you accomplish in all your lifestyle pursuits.